aspB [2017-8-11 16:0:3]

aspartate transaminase

locus: BSU22370

pI: 5.30

mw: 42.93 kDa

protein length: 393 aa

gene length: 1179 bp

function: biosynthesis of aspartate

product: aspartate transaminase

essential: no

ec: 2.6.1.1

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.5|Biosynthesis/ acquisition of aspartate/ asparagine]

Gene

Coordinates: 2,347,660 → 2,348,841

The protein

Catalyzed reaction/ biological activity

• L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate (according to Swiss-Prot)

Protein family

• TCR/tet family (according to Swiss-Prot)

[SW|Cofactors]

• PLP

Structure

• [PDB|1J32] (from ''Phormidium lapideum'', 45% identity, 66% similarity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

additional information

• belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]

Expression and Regulation

Operons

• genes: [gene|08F907C6F47BDEB4DC9A9F136CDC6A4063AC0140|ypmA]-[gene|D3629004F3B54D11566AE15227174F9EB7784201|tseB]-[gene|AE802E1D4F827DED3A5D953C7D034E6A3554C45F|aspB]
  description: [Pubmed|29995990,22383849]

• genes: [gene|D3629004F3B54D11566AE15227174F9EB7784201|tseB]-[gene|AE802E1D4F827DED3A5D953C7D034E6A3554C45F|aspB]
  description: [Pubmed|22383849]

  regulation

  • constitutive

References

• 15378759,28232482